What is Glutathione?

Glutathione (GSH) is a tripeptide. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione, an antioxidant, protects cells from toxins such as free radicals.

Thiol groups are kept in a reduced state at a concentration of approximately ~5 mM in animal cells. In effect, glutathione reduces any disulfide bonds formed within cytoplasmic proteins to cysteines by acting as an electron donor. Glutathione is found almost exclusively in its reduced form, since the enzyme that reverts it from its oxidized form (GSSG), glutathione reductase, is constitutively active and inducible upon oxidative stress. In fact, the ratio of reduced glutathione to oxidized glutathione within cells is often used scientifically as a measure of cellular toxicity.

Glutathione is not an essential nutrient since it can be synthesized from the amino acids L-cysteine, L-glutamate and glycine.

It is synthesized in two adenosine triphosphate-dependent steps:

• First, gamma-glutamylcysteine is synthesized from L-glutamate and cysteine via the enzyme gamma-glutamylcysteine synthetase (a.k.a. glutamate cysteine ligase, GCL). This reaction is the rate-limiting step in glutathione synthesis.
• Second, glycine is added to the C-terminal of gamma-glutamylcysteine via the enzyme glutathione synthetase.

Glutamate cysteine ligase (GCL) is a heterodimeric enzyme composed of a catalytic (GCLC) and modulatory (GCLM) subunit. GCLC constitutes all the enzymatic activity, whereas GCLM increases the catalytic efficiency of GCLC. Mice lacking GCLC (i.e., all de novo GSH synthesis) die before birth. Mice lacking GCLM demonstrate no outward phenotype, but exhibit marked decrease in GSH and increased sensitivity to toxic insults.

While all cells in the human body are capable of synthesizing glutathione, liver glutathione synthesis has been shown to be essential. Following birth, mice with genetically-induced loss of GCLC (i.e., GSH synthesis) only in the liver die within 1 month of birth.

More About Glutathione

Filipinos have a long-standing fascination with “fair” skin. Most of our actors and personalities possess smooth, flawless and light complexions that are not natural to our country and a race such as ours. Thus, many of us who are not as “blessed” to have been born with naturally light skin complexions resort to different means of skin whitening.

Like it or not, skin whitening is a multibillion peso industry.  Skin whitening products abound in the market and the distribution of such is a flourishing business. Skin whitening products come in all forms. Skin bleaching soaps and skin whitening lotions and toners have been popular choices of most pigment-challenged Filipinos due to their easy application and cost effectiveness but there is one skin whitening product that is fast gaining leverage with the consumers these days.

Glutathione in the form of skin whitening pills is all the rage today. Glutathione was originally aimed for freeing cells of toxins and free radicals, while the skin whitening is only just a side effect. Glutathione pills are the kind of skin whitening product that can easily be taken and results can be seen in as fast as after three months of use. You can help speed up the process by taking vitamin C along with whitening pills, so that you can also be fair and healthy inside and out. Although pricier than most skin bleaching products, buyers are stocking up on skin whitening pills as some variants not only lighten the skin but also offer other benefits such as weight loss.

Operating or selling your wares on line is a great and hassle-free way to earn and could be a great sideline job in the philippines that will not intrude with your main job. You can reach a wider market without the effort and cost. If you plan to take advantage of the current demand for skin whitening products such as skin whitening pills, here are a few tips on selling whitening pills online:

1. Find suppliers who are reliable. Make sure that you are getting your skin whitening products from sources that not only have large rosters of clients, but are actually experts and have ample knowledge and experience in the field.

2. Once you have found a supplier for your skin whitening products, you can now look for an online store that would host your services. sulit.com.ph, ebay.com.ph, and auction.ph are some of the sites that you can refer to.

3. Become an expert yourself and improve your knowledge of your product. Because you are selling skin whitening products, it would be better if you can give specifics and answer questions regarding its benefits.

4. Encourage satisfied customers to post their testimonials about the skin whitening products that you are selling by posting on your forums. This form of advertising draws in more buyers and validates your product’s effectiveness.

Video about Glutathione!

If you like to distribute this genuine, unique and exclusive product, Please contact me at +63915-1185693 or +63928-9569425  or email me at aim_rene28@yahoo.com.ph .Thank You and Have a Blessed Day and God Bless!!!

"Fake Glutathione" Be ware of this products!!!